Nursing interventions for fifth disease (Erythema Infectiosum)

  1. Ensure adequate fluid intake and encourage rest.
  2. Encourage frequent hand washing.
  3. Administer Acetaminophen (Tylenol) to decrease body temperature. Aspirin (acetylsalicylic acid) is not recommended as it is related to the occurrence of Reye’ syndrome.
  4. Droplet precautions should be implemented if the child is hospitalized. (wearing mask,gloves, eyewear, spacing client in single room)
  5. Intravenous immunoglobulin therapy may be required for chronic anemia in patients who are immunocompromised.
  6. For an acute aplastic crisis, supplemental oxygen and blood transfusions may be necessary.
  7. Nonsteroidal anti-inflammatory drugs (NSAIDs) may be given to relieve fever, malaise, headache, and arthralgia, along with topical antipruritics and antihistamines (which also relieve pruritus) as ordered.
  8. Avoid contact to pregnant women. Parvovirus B19 is teratogenic. It causes severe anemia with congestive heart failure to the fetus.
  9. Inform parents that child may resume school as soon as the rash appears. (the disease is no longer contagious at this time)


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